By Dr Robert Goldman
Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimise the human aging process. Dr Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, and Dr Ronald Klatz, M.D., D.O., A4M President, physician co-founders of the anti-aging medical movement, distil these headlines and provide their commentary.
Mediterranean Foods Boost Heart Health
A number of previous studies have shown the ability of a Mediterranean-style diet – rich in fruits, vegetables, olive oil and nuts – to promote heart health. Miguel-Angel Martinez-Gonzalez, from the University of Navarra in Spain, and colleagues completed a three-month study involving 7,500 men and women with early heart disease risk. Each subject was assigned to one of three groups: a Mediterranean-style diet with virgin olive oil (15 L per three months); a nut group (30 g a day of walnuts, almonds and hazelnuts); a group given educational material about a low-fat diet. As a marker of atherosclerosis, the team measured changes in apolipoprotein (Apo)B, ApoA-I and their ratio. The researchers report significant improvements in these markers, among those subjects who followed the Mediterranean pattern, that is who consumed a diet that included either virgin olive oil or nuts. Specifically, the apolipoprotein ratio among men dropped 5 percent, and fell 16.6 percent among women – both declines suggesting a reduction of cardiometabolic risk.
Dr Klatz observes: Spanish researchers find that a diet rich in olive oil and nuts beats drug therapies for heart disease, adding to the growing body of evidence suggesting the life-extending benefits of a Mediterranean-style diet.
Exercise Promotes Healthy Cellular Signals
Exercise encourages cellular communications among bone, fat and pancreatic cells. Norman Pollack, from Georgia Health Sciences University, and colleagues completed a study of obese children enrolled in after-school exercise programs. The researchers found that 12 weeks of vigorous exercise produced stronger bones, improved insulin sensitivity (reduced diabetes risk) and less of the most-deadly belly (visceral) fat. The team observed that blood levels of the hormone osteocalcin, made by bone-producing osteoblasts, were raised by vigorous exercise, and thereby may explain the response among bone, fat and pancreatic cells.
Remarks Dr Goldman: Finding that vigorous exercise raises osteocalcin levels, a hormone associated with bone heath, insulin sensitivity and fat stores, these researchers elucidate a key mechanism by which physical activity promotes health and longevity.
Cancer-Fighting Food Combination
Myrosinase is an enzyme necessary to form sulforaphane, a compound found abundantly in broccoli that confers cancer-preventative effects. Found in spicy foods, including broccoli sprouts, mustard, horseradish and wasabi, myrosinanse promotes the release of sulforaphane in the digestive system in a form that is most bioavailable to the body. Jenna Cramer, from University of Illinois, and colleagues observed that when fresh broccoli sprouts were eaten with broccoli powder, bioactive compounds were present in the blood 30 minutes later. When these compounds peaked at three hours, they were much higher when the foods were eaten together than when either was eaten alone. Observing that: “Combining broccoli sprouts with the [broccoli] synergistically enhanced the early appearance of [sulforaphane],” the researchers submit that their findings “[offer] insight into the combination of foods for improved health benefits of foods that reduce the risk for cancer.”
Comments Dr Klatz: Spicing up broccoli with broccoli sprouts, mustard, horseradish or wasabi is a simple and tasty way to boost each food’s individual cancer-fighting power, as well as promote optimal digestive absorption.
Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
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